Human performance, public health, biology, and the science of living well.
Researchers at the National Institutes of Health have identified a brain-cell signaling pathway that helps explain how semaglutide drives weight loss in mice, according to an official announcement from NIH researchers. The work points to a possible way to extend the effects of GLP-1 drugs, while also giving scientists a closer look at why responses…
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A study in Psychological Medicine has found that prucalopride, a drug used to treat chronic constipation, improved several cognitive test results in adults with a history of depression. Researchers from the University of Birmingham and the University of Oxford tested whether activating a serotonin receptor found in the brain could ease the memory and concentration…
Researchers at Cornell University and the University of Washington have identified a potential way to help immunotherapy reach a rare liver cancer that often affects young people. Their study in Gastroenterology suggests that the FDA-approved drug AMD3100 can help release immune cells that become stranded inside fibrolamellar carcinoma tumors. The finding matters because fibrolamellar carcinoma…
A study in Neuron involving 41 healthy volunteers found that slow breathing with a longer exhale can shift heart activity, change reward processing in the brain and make people more likely to choose riskier options. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke, known as DIfE and Charité – Universitätsmedizin Berlin showed that a…
