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Human performance, public health, biology, and the science of living well.

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The blood pressure diet linked to sharper aging brains

A study in JAMA Neurology found that several healthy eating patterns were linked to better brain aging, with one familiar heart-health plan standing out. In a long-running analysis led by researchers affiliated with Harvard T.H. Chan School of Public Health, the DASH diet showed the strongest association with lower risk of later-life subjective cognitive decline.…

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NIH Launches New Office To Speed Human-Based Research and Reduce Animal Use

The National Institutes of Health has launched a new office designed to accelerate human-based biomedical research across the agency. The Office of Research Innovation, Validation and Application, known as ORIVA, will coordinate efforts to develop, validate and scale technologies that can better reflect human biology. The announcement places human-based research technologies near the center of…

Laboratory mouse research

A Sugar-Free Low-Fat Diet Triggered a Surprising Gut and Liver Shift in Mice

Twelve mice, two low-fat diets and 16 weeks of feeding revealed an unexpected biological pattern. A study in Frontiers in Immunology found that mice eating a sucrose-free low-fat diet developed changes in gut bacteria, blood sugar control, intestinal inflammation and liver health. The work was led by researchers primarily affiliated with Dasman Diabetes Institute in…