Human performance, public health, biology, and the science of living well.
The National Institutes of Health has opened a long-awaited clinical question: can a purified compound from kratom be studied safely in people as a possible treatment for opioid use disorder? NIH announced on June 1, 2026, that its Investigational New Drug application for mitragynine has taken effect with the U.S. Food and Drug Administration. The…
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A study in JAMA Neurology found that several healthy eating patterns were linked to better brain aging, with one familiar heart-health plan standing out. In a long-running analysis led by researchers affiliated with Harvard T.H. Chan School of Public Health, the DASH diet showed the strongest association with lower risk of later-life subjective cognitive decline.…
A study in Psychological Medicine has found that prucalopride, a drug used to treat chronic constipation, improved several cognitive test results in adults with a history of depression. Researchers from the University of Birmingham and the University of Oxford tested whether activating a serotonin receptor found in the brain could ease the memory and concentration…
Researchers at Cornell University and the University of Washington have identified a potential way to help immunotherapy reach a rare liver cancer that often affects young people. Their study in Gastroenterology suggests that the FDA-approved drug AMD3100 can help release immune cells that become stranded inside fibrolamellar carcinoma tumors. The finding matters because fibrolamellar carcinoma…
